Definition of "at stake"

I see my reputation is at stakeMy fame is shrewdly gored.

c. 1602, William Shakespeare, “The Tragedie of Troylus and Cressida”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, [Act III, scene iii]

How, Lucia, wou’dst thou have me sink awayIn pleasing Dreams, and lose my self in Love,When ev’ry moment Cato’s Life’s at Stake?

1712 (date written), [Joseph] Addison, Cato, a Tragedy. […], London: […] J[acob] Tonson, […], published 1713, Act V, scene i, page 14

[…] as I have a great deal more at stake on this point than anybody else can have, I think it rather unnecessary in you to be advising me.

1817 (date written), [Jane Austen], chapter V, in Persuasion; published in Northanger Abbey: And Persuasion. […], volumes (please specify |volume=III or IV), London: John Murray, […], 20 December 1817 (indicated as 1818)